DASON Digest

By Duke Antimicrobial Stewardship Outreach Network (DASON)

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Episodes: 136

Description

The DASON Digest features engaging conversations with experts in infectious diseases and antimicrobial stewardship covering a variety of topics. New episodes of the Digest are published every other Friday. Subscribe to follow along with our latest content. For more information about DASON, please visit https://dason.medicine.duke.edu.

Episode Date
Ep.136 – Convenience vs. Care: Rethinking IV Push Cefepime in Critically Ill Pseudomonas Patients
May 08, 2026
Ep.135 – Bugging Out: Antimicrobial Updates in Sepsis Care
Apr 24, 2026
Ep.134 – When Antibiotics Get Lost in Transition: Errors Moving from Hospital to Skilled Nursing Facility
Apr 10, 2026
Ep.133 – Beyond the Cardinal Symptoms: Evaluating the Latest Antibiotic COPDE Treatment Criteria
Mar 27, 2026
Ep.132 – The Science of Antibiotic Decisions: Physician Antibiotic Choices for Community Infections
Mar 13, 2026
Ep.131 – When a UTI Isn't Just a UTI: Why the Right Diagnosis Changes Everything
Feb 27, 2026
Ep.130 – Bugs in the Belly: Optimization, Dosing, and Better Outcomes
Feb 13, 2026
Improving Antibiotic Prescribing for Acute Bacterial Sinusitis in 7 Seconds
Jan 30, 2026
Navigating Vaccine Changes: Insights and Updates from the Vaccine Integrity Project
Jan 16, 2026
Ep.127 – Narrowing the Spectrum: De-Escalation Without Compromise
Jan 04, 2026
Three Stewardship Interventions Hospitals Can Steal for 2026
Dec 19, 2025
Ep.125 – Stewardship in Action: Short Courses and Oral Transitions
Dec 05, 2025
Ep.124 – Words Matter: Tackling Fluconazole Overuse
Nov 14, 2025
Down with Cefdinir! Cefdinir versus Cephalexin for uncomplicated UTIs
Oct 31, 2025
A Global Perspective on Antimicrobial Resistance
Oct 03, 2025
Ep.121 – PEP Talk: Navigating the New HIV Occupational Guideline
Sep 19, 2025
Antibiotic Dosing in Obesity: What the Largest PK Review Reveals
Sep 08, 2025
Ep.119 – New Rules for Old Infections: What the DOTS Trial Tells Us
Aug 22, 2025
Ep.118 – Combatting unnecessary ASB treatment through diagnostic stewardship – which approach works?
Aug 08, 2025
Ep.117 – Nurse-Driven PEN-FAST Allergy De-labeling
Jul 25, 2025
Ep.116 – Cascade Reporting Under the Microscope: Two Sides, One Debate
Jul 14, 2025
Ep.115 – Septic Shock and AKI: Do we still need to worry about piperacillin-tazobactam?
Jun 27, 2025
Ep.114 – Procalcitonin in Practice: Evaluating Its Impact on CAP Management
Jun 13, 2025
Ep.113 – Are You Ready for It? Assessing Cephalosporin Allergies with the CEPH-FAST Score
May 30, 2025
Ep.112 – (Re)moving the needle: implementation of an institutional IV to PO treatment guidance for bone and joint infections
May 16, 2025
Ep.111 – Sole Support: Using Clinical Decision Support Solutions to Improve Care for Patients Inpatients with Diabetic Foot Infections
May 02, 2025
SBP Prophylaxis: What We’re Doing, Why We’re Doing It… and Should We Keep Doing It?
Apr 18, 2025
Short and Sweet: Is short course appropriate for uncomplicated Streptococcal bacteremia?
Apr 04, 2025
Ep.108 – Guideline-Driven Success: Standardizing Care for Gram-Negative Bloodstream Infections
Mar 21, 2025
Ep.107 – Blood Culture Stewardship: Post Shortage Lessons
Mar 07, 2025
Ep.106 – Less is More-Dazole? Metronidazole twice daily versus three times daily for B. fragilis bacteremia
Feb 21, 2025
Ep.105 – Antibiotic De-escalation in Sepsis Patients
Feb 07, 2025
Ep.104 – Testing Troubles: Navigating C. difficile confusion
Jan 24, 2025
The BALANCE Trial: 7 vs 14 Days for Bloodstream Infection
Jan 10, 2025
Ep.102 – Bug in a Mug: Should we be worried about hospital coffee machines?
Dec 20, 2024
Ep.101 – Decoding DxEx: the CDC Core Elements of Hospital Diagnostic Excellence
Dec 06, 2024
Ep.100 – Episode 100: A Celebration of Stewardship
Nov 22, 2024
Ep.99 – Unexpected Findings: Ertapenem in Surgical Prophylaxis
Nov 08, 2024
Ep.98 – Choosing Wisely: Antibiotic Decisions in Outpatient Community-Acquired Pneumonia
Oct 25, 2024
Ep.97 – A Multicenter Retrospective Study Evaluating Intravenous to Oral Antibiotic Stepdown for Uncomplicated Streptococcal Bacteremia
Oct 11, 2024
Ep.96 – Update Alert! IDSA Resistant Gram-negative Guidance Version 4.0
Sep 27, 2024
Waiting on a Culture: Impact of pharmacist-led microresult follow-up post-discharge
Sep 13, 2024
Ep.94 – Rethinking Daptomycin Dosing: New data on fixed dose daptomycin
Aug 30, 2024
Ep.93 – Return of the Penicillin Allergy Label
Aug 20, 2024
Ep.92 – Is One Better Than the Other? Analyzing surrogates for oral cephalosporin susceptibilities
Aug 02, 2024
Is ID the Consult of Fear?
Jul 19, 2024
Ep.90 – It Goes On and On and On: Reviewing the new RCT for Continuous infusion vs. Intermittent infusion Beta-lactams
Jun 21, 2024
Ep.89 – Infectious Disease Consultations: Can AI Really Replace Human Experts?
Jun 07, 2024
Ep.88 – Is the debate back?: A retrospective study in patients with sepsis who received piperacillin-tazobactam vs. cefepime
May 24, 2024
Ep.87 – BCI(De-escalation): The Impact of Rapid Diagnostics and Stewardship Intervention on Treatment of Contaminated Blood Cultures
May 10, 2024
Ep.86 – PEN-FAST and Furious: The efficacy of the PEN-FAST tool in de-labeling previously reported penicillin allergies
Apr 26, 2024
Ep.85 – The devil's in the defaults: the impact of eliminating default durations of therapy
Apr 12, 2024
Ep.84 – Navigating the LAByrinth: Updates in Antibacterial Susceptibility Testing
Apr 05, 2024
Ep.83 – Incorporating Adverse Event Feedback Into Antibiotic Stewardship
Mar 15, 2024
Ep.82 – Optimizing the use of the GI Panel and strategies to improve appropriate testing
Mar 01, 2024
Ep.81 – Which of Active vs Passive Response to Rapid Diagnostic Blood Culture Results
Feb 19, 2024
Ep.80 – Exploring the Microbiome: Pertinent details from a phase 1 study exploring omadacycline in healthy guts
Feb 02, 2024
Ep.79 – It’s All in the Dose: High-dose oral beta-lactams for bacteremic UTIs due to Enterobacterales
Jan 19, 2024
Ep.78 – Source Specific Sepsis Order Sets Lead to Improved Empiric Therapy in the ED
Jan 05, 2024
Ep.77 – Optimizing Outpatient Ordering
Dec 15, 2023
Ep.76 – Ending VAP: is vaporizing antibiotics the answer?
Dec 01, 2023
Ep.75 – Febrile Podcast: Being a Stewie
Nov 20, 2023
Ep.74 – Neurotoxicity vs Nephrotoxicity: A Look at the Comparative Safety of Cefepime and Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection
Nov 03, 2023
Ep.73 – Analyzing Antibiograms: Reassessing a major tool
Oct 20, 2023
Ep.72 – Hit me with your best shot! Tools to select the best empiric therapy in complicated UTIs
Sep 29, 2023
Ep.71 – Emphasizing Health Equity
Sep 15, 2023
Ep.70 – Can we FINALLY stop antibiotics in culture negative serious infections?
Sep 01, 2023
Ep.69 – Creating Impactful, Feasible, Actionable, and Measurable Stewardship Interventions
Aug 18, 2023
Ep.68 – Don’t be so Negative! A Look at GN-BSI in the US
Aug 04, 2023
Ep.67 – Rx for Success: Tackling Penicillin Allergy De-Labelling in our Hospitals
Jul 21, 2023
Ep.66 – The Necrotizing Soft Tissue Infection Conundrum: Vancomycin Plus Clindamycin vs. Linezolid
Jul 07, 2023
Ep.65 – Plagued by Probiotics?
Jun 23, 2023
Ep.64 – SSI Compendium Update
Jun 09, 2023
Ep.63 – Antibiotic Spectrum Scores
May 26, 2023
Ep.62 – Pip-Tazo: A Pancreatic Panacea?
May 12, 2023
Ep.61 – Antimicrobial susceptibility testing: An updated primer for clinicians in the era of antimicrobial resistance: Insights from the Society of Infectious Diseases Pharmacists
Apr 28, 2023
Ep.60 – Hydrocortisone in Severe Community-Acquired Pneumonia
Apr 14, 2023
Ep.59 – Prophylaxis Progress Report
Mar 31, 2023
Ep.58 – RSV vaccines coming: Its ok to be excited
Mar 17, 2023
Ep.57 – A Guide to Diagnostic Stewardship
Mar 03, 2023
Ep.56 – Let's take a mindful pause before treating bacteriuria in older adults
Feb 17, 2023
Ep.55 – Discordant C. diff testing results - to treat or not to treat?
Feb 03, 2023
Ep.54 – Stewardship Secrets: Optimizing carbapenem use in our facilities
Jan 20, 2023
Ep.53 – Spellcheck Stewardship: A Happy Holidays from DASON
Jan 06, 2023
Ep.52 – A Decade of Fluoroquinolone Stewardship
Dec 09, 2022
Review of the CDC's Antibiotic Use Report - 2022
Nov 24, 2022
Streptococcal Bacteremia and the Risk of Infective Endocarditis
Nov 11, 2022
Stewardship Practices at US Hospitals
Oct 28, 2022
The DETOURS Study - A Chat with the Author
Oct 14, 2022
Ep.47 – A Novel Metric to Measure Antibiotic Use and Spectrum of Activity
Sep 30, 2022
Ep.46 – SSI Rates Among Patients Receiving Elective Colorectal Surgery with Beta-Lactam vs. Non-Beta-Lactam-Based Antimicrobial Prophylaxis
Sep 09, 2022
Ep.45 – Let's Talk About Surgical Prophylaxis
Aug 26, 2022
Ep.44 – Antibiotic Effects on the Gut Microbiome & Resistome: It’s Worse than We Thought - An Interview with Dr. Jennie Kwon
Aug 12, 2022
Ep.43 – Less is More: Reducing Unnecessary Antibiotic Use for Asymptomatic Bacteriuria
Jul 29, 2022
Ep.42 – A Chat With the Author: Network- and Health System-guided Stewardship
Jul 15, 2022
Ep.41 – Antibiotic Overuse and Stewardship at Hospital Discharge
Jul 01, 2022
Ep.40 – Reducing Antibiotic Use for Upper Respiratory Infections in Outpatients
Jun 17, 2022
Ep.39 – Stewardship Opportunities Upon Hospital Discharge
Jun 03, 2022
Ep.38 – If you have to: Non-antibiotic prophylactic treatment for recurrent UTI
May 20, 2022
Ep.37 – Outpatient Stewardship for UTIs: Reducing Fluoroquinolone Use
May 06, 2022
Ep.36 – Antibiograms for Escalation: What’s the Application?
Apr 22, 2022
Ep.35 – The Waiting Game: Time Between Blood Culture Sets
Apr 08, 2022
Ep.34 – The Role of the Antimicrobial Stewardship Program in Pandemic Response
Mar 25, 2022
Ep.33 – Oral Cephalosporins vs First-line Agents for Outpatients with Pyelonephritis
Mar 11, 2022
Ep.32 – Vancomycin Monitoring: Are We Below the Curve? A Discussion with Experts
Feb 25, 2022
Ep.31 – Systems Say Go: Assessing Antibiotic Prescribing After Removal of a Penicillin Allergy Alert
Feb 11, 2022
Ep.30 – Engaging Nurse Stewards
Jan 28, 2022
Ep.29 – Simplifying the Management of Neurosyphilis
Jan 14, 2022
Ep.28 – COVID Vaccines - Let's Keep Myocarditis in Perspective
Dec 17, 2021
Ep.27 – Molnupiravir – Finally, an Oral Option for Outpatients with COVID-19
Dec 09, 2021
Ep.26 – The Status of Antimicrobial Stewardship in the US
Dec 09, 2021
Ep.25 – Race to Start: Beta-lactams or Vancomycin First for Bacteremia?
Dec 09, 2021
Ep.24 – MSSA Bacteremia: Cefazolin, Final Answer
Dec 09, 2021
Ep.23 – Just for Men: An Update on the Management of UTI
Dec 09, 2021
Ep.22 – 7 Day Treatment Over 14 Days for Enterobacterales Bacteremia, Not Just Non-inferior Anymore!
Dec 09, 2021
Ep.21 – From the Front Lines: Impact of Handshake Stewardship in the ICU
Dec 09, 2021
Ep.20 – Addition By Subtraction: Optimizing Antibiotic Durations at Hospital Discharge
Dec 09, 2021
Ep.19 – Real Talk with DASON: COVID-19 Vaccines
Dec 09, 2021
Ep.18 – Ideas for Antimicrobial Stewardship in the ED
Dec 09, 2021
Ep.17 – Duration of therapy for Prosthetic Joint Infections, review of a potential game changer study with Dr. Ted Hendershot
Dec 09, 2021
Ep.16 – Metronidazole-associated Neurologic Events
Dec 09, 2021
Ep.15 – Estimated Clinical and Economic Impact of Reducing Blood Culture Contamination
Dec 09, 2021
Ep.14 – Preoperative Beta-lactam Allergy Intervention
Dec 09, 2021
Ep.13 – Strategies to Optimize Outpatient Antibiotic Prescribing for UTIs
Dec 09, 2021
Ep.12 – De-Escalation of Broad-Spectrum Antibiotics After Negative Cultures in Patients Admitted with Pneumonia – We Have Work to Do
Dec 09, 2021
Ep.11 – Short-Course Antibiotics: Best Practice Advice from The American College of Physicians
Dec 09, 2021
Ep.10 – Community Acquired Pneumonia: It's All About the Numbers
Dec 09, 2021
Ep.9 – Vancomycin vs Daptomycin – An Old Rival – The Battle Continues
Dec 09, 2021
Ep.8 – The Nose Knows: Using Nasal MRSA PCR to De-Escalate Vancomycin
Dec 09, 2021
Ep.7 – Discussing the DRIP Score
Dec 09, 2021
Ep.6 – Cefiderocol: Seeking Another Option for Serious Gram-Negative Infections
Dec 09, 2021
Ep.5 – Antibiotics for Appendicitis: Ready for Prime Time?
Dec 09, 2021
Ep.4 – Antimicrobial Stewardship Guidance for COVID-19 Patients
Dec 09, 2021
Ep.3 – COVID-19 mRNA Vaccine: Myths and Common Questions
Dec 09, 2021
Ep.2 – A Preview of the Upcoming Changes to the IDSA C. difficile Treatment Guidelines
Dec 09, 2021
Ep.1 – Optimizing Treatment for ESBL-Producing Pathogens
Dec 09, 2021